Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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121
Tocris Bioscience™ Blasticidin S HCl
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Antibiotic; selection reagent for bis, bsr and BSD transformed cells
123
Tocris Bioscience™ N-Acetylcysteine amide
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Glutathione (GSH) precursor; neuroprotective
| Target | Additional Antioxidant Compounds |
|---|---|
| CAS | 38520-57-9 |
| Chemical Name or Material | (2R)-2-(Acetylamino)-3-mercaptopropanamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C5H10N2O2S |
| Formula Weight | 162.21 |
124
Tocris Bioscience™ Hydroxychloroquine sulfate
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Autophagy inhibitor; also TLR9 inhibitor
| Target | Autophagy-related Compounds |
|---|---|
| CAS | 747-36-4 |
| Purity | >99% |
| Chemical Name or Material | 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C18H28ClN3O5S |
| Formula Weight | 433.95 |
125
Tocris Bioscience™ A 410099.1 amide-PEG5-amine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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IAP ligand with PEG linker and terminal amine for onward chemistry
126
Tocris Bioscience™ TFM-4AS-1
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CAS: 188589-61-9 Molecular Formula: C27H33F3N2O2
| CAS | 188589-61-9 |
|---|---|
| Molecular Formula | C27H33F3N2O2 |
127
Tocris Bioscience™ Paroxetine maleate
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Highly potent and selective 5-HT uptake inhibitor
| Inhibitors | Paroxetine maleate |
|---|---|
| Product Type | Paroxetine maleate |
| Molecular Weight (g/mol) | 445.44 |
| Purity | >99% |
128
Tocris Bioscience™ 6877002
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CD40-TRAF6 interaction inhibitor
| Target | Additional Cytokine Receptor Products |
|---|---|
| CAS | 433249-94-6 |
| Purity | >99% |
| Chemical Name or Material | 3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C17H17NO |
| Formula Weight | 251.32 |
129
Tocris Bioscience™ VH 032 amide-PEG3-acid
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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VH 032-PEG3-CH2CH2COOH
130
Tocris Bioscience™ Kynurenic acid sodium salt
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Sodium salt of kynurenic acid (Cat. No. 0223)
131
Tocris Bioscience™ Letrozole
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 112809-51-5 Molecular Formula: C17H11N5
| CAS | 112809-51-5 |
|---|---|
| Molecular Formula | C17H11N5 |
132
Tocris Bioscience™ T 0901317
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 293754-55-9 Molecular Formula: C17H12F9NO3S
| CAS | 293754-55-9 |
|---|---|
| Molecular Formula | C17H12F9NO3S |
133
Tocris Bioscience™ VH 032 amide-alkylC4-amine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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PROTACs (Proteolysis Targeting Chimeras)
134
Tocris Bioscience™ GW 0742
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 317318-84-6 Molecular Formula: C21H17F4NO3S2
| CAS | 317318-84-6 |
|---|---|
| Molecular Formula | C21H17F4NO3S2 |
135
Tocris Bioscience™ DBZ
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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γ-secretase inhibitor; inhibits Notch pathway
| CAS | 209984-56-5 |
|---|---|
| Chemical Name or Material | DBZ |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H23F2N3O3 |
| Formula Weight | 463.48 |
| Assay Percent Range | >98% |